Carbon monoxide and Compound A measurements with desflurane and sevoflurane anaesthesia in humans: an observational study
| ISRCTN | ISRCTN84188372 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN84188372 |
| Secondary identifying numbers | N/A |
- Submission date
- 27/06/2007
- Registration date
- 27/06/2007
- Last edited
- 06/08/2021
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Signs and Symptoms
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Plain English Summary
Not provided at time of registration
Contact information
Dr C. Keijzer
Scientific
Scientific
Netherlands Cancer Institute (NKI)
Plesmanlaan 121
Amsterdam
1066 CX
Netherlands
| Phone | +31 (0)20 512 9111 |
|---|---|
| c.keijzer@nki.nl |
Study information
| Study design | Observational, case-control study |
|---|---|
| Primary study design | Observational |
| Secondary study design | Case-control study |
| Study setting(s) | Hospital |
| Study type | Screening |
| Scientific title | Carbon monoxide and Compound A measurements with desflurane and sevoflurane anaesthesia in humans: an observational study |
| Study hypothesis | The purpose of this study is to register the average Carbon monoxide (CO) concentrations in forty patients receiving desflurane or sevoflurane anaesthesia after implementation of a safety protocol to prevent desiccation of the strong base containing absorbent Drägersorb 800 Plus®. |
| Ethics approval(s) | Ethics approval received from the local medical ethics committee |
| Condition | Anaesthesia |
| Intervention | Desflurane or sevoflurane anaesthesia. |
| Intervention type | Drug |
| Pharmaceutical study type(s) | |
| Phase | Not Specified |
| Drug / device / biological / vaccine name(s) | Desflurane, sevoflurane |
| Primary outcome measure | Amount of carbon monoxide or compound A produced. |
| Secondary outcome measures | No secondary outcome measures |
| Overall study start date | 01/08/2005 |
| Overall study end date | 01/10/2006 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Adult |
| Sex | Not Specified |
| Target number of participants | 40 |
| Total final enrolment | 40 |
| Participant inclusion criteria | 1. Non-smoking patients 2. American Society of Anaesthesiologists physical status class 1 to 3 3. Scheduled for a surgical procedure that would last at least ninety minutes |
| Participant exclusion criteria | 1. Younger than 18 years of age 2. Suffering from terminal renal failure |
| Recruitment start date | 01/08/2005 |
| Recruitment end date | 01/10/2006 |
Locations
Countries of recruitment
- Netherlands
Study participating centre
Netherlands Cancer Institute (NKI)
Amsterdam
1066 CX
Netherlands
1066 CX
Netherlands
Sponsor information
Vrije University Medical Centre (VUMC) (The Netherlands)
Hospital/treatment centre
Hospital/treatment centre
Department of Anesthesiology
P.O. Box 7057
Amsterdam
1007 MB
Netherlands
| Website | http://www.vumc.nl/english/ |
|---|---|
"ROR" |
https://ror.org/00q6h8f30 |
Funders
Funder type
Hospital/treatment centre
Vrije University Medical Centre (VUMC) (The Netherlands)
No information available
Results and Publications
| Intention to publish date | |
|---|---|
| Individual participant data (IPD) Intention to share | No |
| IPD sharing plan summary | Not provided at time of registration |
| Publication and dissemination plan | Not provided at time of registration |
| IPD sharing plan |
Study outputs
| Output type | Details | Date created | Date added | Peer reviewed? | Patient-facing? |
|---|---|---|---|---|---|
| Results article | 08/05/2008 | 06/08/2021 | Yes | No |
Editorial Notes
06/08/2021: Publication reference and total final enrolment added.
