Additional identifiers
EudraCT/CTIS number
IRAS number
ClinicalTrials.gov number
Protocol/serial number
N0059122213
Study information
Scientific title
Prospective, randomised, blind study to compare two flushing media on oocyte collection and fertilisation rates after in vitro fertilisation (IVF)
Acronym
Study hypothesis
Prospective, randomised, blind study to compare two flushing media on oocyte collection and fertilisation rates after in vitro fertilisation (IVF). The success rates of human in vitro fertilisation remain disappointingly low, only 25% of couples will take home a baby (HFEA report 1999.) The quality of eggs collected from a woman's ovaries has a significant influence on the implantation potential of any resulting embryos and therefore the chances of a patient becoming pregnant. The aims of this study are:
a. To determine whether the medium used to flush ovarian follicles during egg collection in IVF has an impact on oocyte quality, fertilisation rates and subsequent embryo development
b. To compare the use of a new complex flushing medium (Sydney IVF Follicle Flushing Buffer, COOK) with our current flushing medium, Hartmann's solution (Baxter).
Ethics approval(s)
Not provided at time of registration
Study design
Randomised controlled trial
Primary study design
Interventional
Secondary study design
Randomised controlled trial
Study setting(s)
Hospital
Study type
Other
Patient information sheet
Not available in web format, please use the contact details below to request a patient information sheet
Condition
Pregnancy and Childbirth: In vitro fertilisation (IVF)
Intervention
Compare the use of new complex flushing medium (Sydney IVF Follicle Flushing Buffer, COOK) with our current flushing medium, Hartmann's solution (Baxter).
Intervention type
Other
Primary outcome measure
Currently unavailable.
Secondary outcome measures
Not provided at time of registration
Overall study start date
01/10/2002
Overall study end date
01/09/2003
Reason abandoned (if study stopped)
Eligibility
Participant inclusion criteria
Female patients, Assisted Conception Unit.
Participant type(s)
Patient
Age group
Adult
Sex
Female
Target number of participants
Not provided at time of registration
Participant exclusion criteria
Does not meet inclusion criteria
Recruitment start date
01/10/2002
Recruitment end date
01/09/2003
Locations
Countries of recruitment
England, United Kingdom
Study participating centre
University of Sheffield
Sheffield
S10 2SF
United Kingdom
Sponsor information
Organisation
Department of Health (UK)
Sponsor details
Richmond House
79 Whitehall
London
SW1A 2NL
United Kingdom
Sponsor type
Government
Website
Funders
Funder type
Hospital/treatment centre
Funder name
Sheffield Teaching Hospitals NHS Foundation Trust (UK)
Alternative name(s)
Funding Body Type
Funding Body Subtype
Location
Results and Publications
Publication and dissemination plan
Not provided at time of registration
Intention to publish date
Individual participant data (IPD) sharing plan
IPD sharing plan summary
Not provided at time of registration
Study outputs
| Output type | Details | Date created | Date added | Peer reviewed? | Patient-facing? |
|---|---|---|---|---|---|
| Abstract results | results presented at the Association of Clinical Embryologists Annual Meeting | 01/01/2009 | 31/10/2019 | No | No |