A Randomised Trial Comparing External Beam Radiotherapy Alone With External Beam Radiotherapy Plus Intraluminal Irradiation for Palliation in Lung Cancer
| ISRCTN | ISRCTN83218866 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN83218866 |
| Secondary identifying numbers | ILT-2 |
- Submission date
- 19/08/2002
- Registration date
- 19/08/2002
- Last edited
- 08/04/2015
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Cancer
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Record updated in last year
Plain English Summary
Not provided at time of registration
Contact information
- - -
Scientific
Scientific
UKCCCR Register Co-ordinator
MRC Clinical Trials Unit
222 Euston Road
London
NW1 2DA
United Kingdom
Study information
| Study design | Randomised controlled trial |
|---|---|
| Primary study design | Interventional |
| Secondary study design | Randomised controlled trial |
| Study setting(s) | Hospital |
| Study type | Treatment |
| Scientific title | A Randomised Trial Comparing External Beam Radiotherapy Alone With External Beam Radiotherapy Plus Intraluminal Irradiation for Palliation in Lung Cancer |
| Study hypothesis | Not provided at time of registration |
| Ethics approval(s) | Not provided at time of registration |
| Condition | Lung (non-small cell) cancer |
| Intervention | 1. Schedule A: External beam radiotherapy, a maximum subcutaneous dose of 3250 cGy given in eight fractions over 10 days with a margin of 2 cm around the tumour. 2. Schedule B: External beam radiotherapy, a maximum subcutaneous dose of 3250 cGy given in eight fractions over 10 days with a margin of 2 cm around the tumour. Followed by intraluminal radiotherapy, a single dose of 1500 cGy to be given on the last day of external beam radiotherapy. |
| Intervention type | Other |
| Primary outcome measure | Not provided at time of registration |
| Secondary outcome measures | Not provided at time of registration |
| Overall study start date | 01/01/2000 |
| Overall study end date | 31/12/2005 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Adult |
| Sex | Both |
| Target number of participants | Not provided at time of registration |
| Participant inclusion criteria | 1. Biopsy proven non-small cell lung cancer 2. Fit to receive bronchoscopy 3. Fit to receive external beam radiotherapy 4. Any age 5. Shortness of breath, cough, haemoptysis, dysphagia or chest pain resulting from a primary bronchial tumour 6. No previous or concomitant malignancy, except basal cell carcinomas 7. No symptomatic metastases requiring external beam radiotherapy 8. No previous chest irradiation for lung cancer 9. No bilateral lung tumours or tracheal tumours |
| Participant exclusion criteria | Not provided at time of registration |
| Recruitment start date | 01/01/2000 |
| Recruitment end date | 31/12/2005 |
Locations
Countries of recruitment
- England
- United Kingdom
Study participating centre
MRC Clinical Trials Unit
London
NW1 2DA
United Kingdom
NW1 2DA
United Kingdom
Sponsor information
UK Co-ordinating Committee for Cancer Research (UKCCCR)
Government
Government
MRC Clinical Trials Unit
222 Euston Road
London
NW1 2DA
United Kingdom
"ROR" |
https://ror.org/054225q67 |
|---|
Funders
Funder type
Research organisation
Cancer organisations (UK)
No information available
Results and Publications
| Intention to publish date | |
|---|---|
| Individual participant data (IPD) Intention to share | No |
| IPD sharing plan summary | Not provided at time of registration |
| Publication and dissemination plan | Not provided at time of registration |
| IPD sharing plan |
