Contact information
Type
Scientific
Contact name
Prof Adnan Custovic
ORCID ID
Contact details
North West Lung Research Centre
Wythenshawe Hospital
Southmoor Road
Manchester
M23 9LT
United Kingdom
+44 (0)161 291 2494
adnan.custovic@manchester.ac.uk
Additional identifiers
EudraCT/CTIS number
IRAS number
ClinicalTrials.gov number
Secondary identifying numbers
N/A
Study information
Scientific title
Manchester Asthma and Allergy Study
Acronym
MAAS
Study hypothesis
Birth cohort study investigating the development of asthma and allergic disease
Ethics approval(s)
1. Age 0 - 5 years follow up, ERP/94/032, approval received on 24/03/1994
2. Age 5 - 8 years follow up, SOU/00/258 and SOU/00/259, approval received on 20/12/2000
3. Age 8 - 11 years follow up, 03/SM/400, approval received on 05/12/2003
Study design
Prospective observational birth cohort study
Primary study design
Observational
Secondary study design
Cohort study
Study setting(s)
Not specified
Study type
Other
Patient information sheet
Not available in web format, please use the contact details below to request a patient information sheet
Condition
Asthma and allergy
Intervention
This is a prospective, observational birth cohort study, which includes investigating environmental exposures, immune responses, behaviour or family functioning, genetic epidemiology, pulmonary physiology and clinical outcomes
Intervention type
Other
Primary outcome measure
1. Asthma at age 5, 8, 11 and 14 years
2. Sensitisation at age 1, 3, 5, 8, 11 and 14 years
3. Allergies (e.g. hay fever) at age 5, 8, 11 and 14 years
Secondary outcome measures
1. Wheeze and eczema at age 1, 3, 5, 8, 11 and 14 years
2. Healthcare utilisation by age 8 - 11 years
Overall study start date
01/09/1995
Overall study end date
01/06/2019
Reason abandoned (if study stopped)
Eligibility
Participant inclusion criteria
Children born at Wythenshawe Hospital, Manchester and Stepping Hill Hospital, Stockport between January 1996 and April 1998
Participant type(s)
Patient
Age group
Child
Sex
Both
Target number of participants
1250
Participant exclusion criteria
Premature birth <32 weeks gestation
Recruitment start date
01/09/1995
Recruitment end date
01/06/2019
Locations
Countries of recruitment
England, United Kingdom
Study participating centre
Wythenshawe Hospital
Manchester
M23 9LT
United Kingdom
Sponsor information
Organisation
Wythenshawe Hospital (UK)
Sponsor details
c/o Andrew Maines
Research and Development Directorate
ERC Building
Wythenshawe Hospital
Southmoor Road
Manchester
M23 9LT
England
United Kingdom
+44 (0)161 291 5775
andrew.maines@manchester.ac.uk
Sponsor type
Hospital/treatment centre
Website
ROR
Funders
Funder type
Charity
Funder name
Asthma UK (UK)
Alternative name(s)
Asthma UK, Asthma + Lung UK
Funding Body Type
private sector organisation
Funding Body Subtype
Other non-profit organizations
Location
United Kingdom
Funder name
Moulton Charitable Trust (UK)
Alternative name(s)
Funding Body Type
Funding Body Subtype
Location
Results and Publications
Publication and dissemination plan
Not provided at time of registration
Intention to publish date
Individual participant data (IPD) Intention to share
No
IPD sharing plan
IPD sharing plan summary
Not provided at time of registration
Study outputs
| Output type | Details | Date created | Date added | Peer reviewed? | Patient-facing? |
|---|---|---|---|---|---|
| Results article | results | 15/06/2008 | Yes | No | |
| Results article | results | 01/06/2010 | Yes | No | |
| Results article | results | 01/12/2015 | Yes | No | |
| Results article | results | 15/10/2018 | Yes | No |