Bordetella pertussis serology in pregnancy
| ISRCTN | ISRCTN14204141 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN14204141 |
| Secondary identifying numbers | MEC/02/14 P02.205; NTR448 |
- Submission date
- 27/02/2007
- Registration date
- 27/02/2007
- Last edited
- 05/01/2021
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Pregnancy and Childbirth
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Plain English Summary
Not provided at time of registration
Contact information
Dr J C M van Huisseling
Scientific
Scientific
Groene Hart Hospital
P.O. Box 1098
Gouda
2800 BB
Netherlands
| Phone | +31 (0)18 250 5050 |
|---|---|
| hans.van.huisseling@ghz.nl |
Study information
| Study design | Observational, single centre, cross-sectional survey |
|---|---|
| Primary study design | Observational |
| Secondary study design | Cross sectional study |
| Study setting(s) | Hospital |
| Study type | Screening |
| Scientific title | Bordetella pertussis serology in pregnancy |
| Study acronym | Kinkzwang |
| Study hypothesis | About 6% of the population between three and 79 years suffers each year of a B. pertussis infection, including pregnant women. These women are a source of infection for their newborn babies. |
| Ethics approval(s) | Approval received from the local medical ethics committee (Commissie Medische Ethiek, Leids Universitair Medisch Centrum, Leiden) (ref: P02-205). |
| Condition | B. pertussis infection in pregnancy |
| Intervention | Serology for Immunoglobulin G (IgG) against pertussis toxin in blood of the mother and cord blood. The test used is the test as used by the National Institute for Public Health and the Environment (RIVM) (The Netherlands). |
| Intervention type | Other |
| Primary outcome measure | 1. Positive B. pertussis serology 2. Cata questionnaires |
| Secondary outcome measures | No secondary outcome measures |
| Overall study start date | 01/08/2002 |
| Overall study end date | 01/06/2006 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Adult |
| Sex | Female |
| Target number of participants | 500 |
| Participant inclusion criteria | All pregnant women delivering at the department of gynecology and obstetrics of the Groene Hart Hospital. |
| Participant exclusion criteria | Does not comply with the above inclusion criteria |
| Recruitment start date | 01/08/2002 |
| Recruitment end date | 01/06/2006 |
Locations
Countries of recruitment
- Netherlands
Study participating centre
Groene Hart Hospital
Gouda
2800 BB
Netherlands
2800 BB
Netherlands
Sponsor information
Groene Hart Hospital (The Netherlands)
Hospital/treatment centre
Hospital/treatment centre
Department of Gynaecology and Obstetrics
P.O. Box 1098
Gouda
2800 BB
Netherlands
| Website | http://www.ghz.nl/ |
|---|---|
"ROR" |
https://ror.org/0582y1e41 |
Funders
Funder type
Government
National Institute for Public Health and the Environment (RIVM) (The Netherlands) - performing the serology
No information available
All other costs are covered by the principal investigator.
No information available
Results and Publications
| Intention to publish date | |
|---|---|
| Individual participant data (IPD) Intention to share | No |
| IPD sharing plan summary | Not provided at time of registration |
| Publication and dissemination plan | Not provided at time of registration |
| IPD sharing plan |
Study outputs
| Output type | Details | Date created | Date added | Peer reviewed? | Patient-facing? |
|---|---|---|---|---|---|
| Results article | results | 01/07/2009 | 05/01/2021 | Yes | No |
Editorial Notes
05/01/2021: Publication reference added.
